Chiefs vs Colts: match preview on 21 September 2026

Chiefs are favourites, and the gap in recent results makes that straightforward. They have taken four points from their last four games with a win, a tie and two losses, while the Colts have managed just one point from a tie and three defeats. The Chiefs scored 67 points and conceded 55; the Colts scored 58 and let in 113. Colts have leaked 58 more points than Chiefs.

The Chiefs' attack has shown bursts of power. Their 31:10 victory over the Broncos was a statement win, and even in their losses they managed to score. The Colts, by contrast, have been outscored heavily in three of their four matches. They lost 23:41 to the Ravens, 16:25 to the Lions and 6:34 to the Falcons. Only against the Patriots did they hold on for a 13:13 tie away from home.

Patrick Mahomes has returned from a knee injury sustained in December 2025 and has been back in training since early September 2026. His presence gives the Chiefs a familiar structure at quarterback.

The Chiefs win. The Chiefs have not been dominant, but they have been competitive. The Colts have been consistently outplayed. A Chiefs win is the most likely outcome.

A Colts tie or win hinges on tempo control and limiting Chiefs chances. The Colts have shown they can tie games when they defend well, as against the Patriots. If they replicate that approach and the Chiefs fail to convert their chances, the match could end in a tie or even a Colts victory.